Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 2.580


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA7chr7_-_271626880.741.1e-03Click!
HOXB7chr17_-_440429240.485.7e-02Click!
HOXB6chr17_-_440373320.467.2e-02Click!
HOXA6chr7_-_271538920.332.1e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_113853790 7.977 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr13_-_101852028 7.040 NM_175929
FGF14
fibroblast growth factor 14
chr1_+_168898898 6.667 PRRX1
paired related homeobox 1
chrX_+_135079461 6.526 NM_001167819
FHL1
four and a half LIM domains 1
chr9_-_14076901 6.138 NFIB
nuclear factor I/B
chr14_+_100365162 6.054 MEG3
maternally expressed 3 (non-protein coding)
chr3_+_174598937 5.987 NM_014932
NLGN1
neuroligin 1
chr1_+_81544432 5.758 LPHN2
latrophilin 2
chrX_+_28515479 4.859 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr7_-_27149750 4.840 NM_019102
HOXA5
homeobox A5
chr4_+_119174947 4.782 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr3_-_64186151 4.752 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr9_+_108665168 4.401 NM_021224
ZNF462
zinc finger protein 462
chr4_-_41579325 3.786


chr12_-_48902692 3.225 NM_001113547
LIMA1
LIM domain and actin binding 1
chr20_+_56369012 3.163


chr1_-_27604656 3.131 WASF2
WAS protein family, member 2
chr2_+_36777336 3.093 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr18_+_30544193 3.067 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr5_-_124108672 3.059 NM_020747
ZNF608
zinc finger protein 608
chr20_+_11846536 3.042 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr7_-_27171600 3.041 HOXA9
homeobox A9
chr9_-_8723893 2.992 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr11_-_27698800 2.985 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr13_-_59223074 2.894


chr10_-_33663305 2.829 NRP1
neuropilin 1
chr20_-_14266200 2.817 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr7_-_27171648 2.800 HOXA9
homeobox A9
chrX_-_33267646 2.793 NM_000109
DMD
dystrophin
chr5_+_174084137 2.775 NM_002449
MSX2
msh homeobox 2
chr4_-_176970372 2.733 GPM6A
glycoprotein M6A
chr4_+_54790020 2.730 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_+_33213111 2.718 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr4_+_81325447 2.679 NM_020226
PRDM8
PR domain containing 8
chr8_-_122722674 2.623 NM_005328
HAS2
hyaluronan synthase 2
chr3_-_55489973 2.607 WNT5A
wingless-type MMTV integration site family, member 5A
chr14_+_85069217 2.567


chr7_-_104696678 2.565 NM_182691
SRPK2
SRSF protein kinase 2
chr9_-_94284455 2.545 ASPN
asporin
chr8_-_15140162 2.544 NM_139167
SGCZ
sarcoglycan, zeta
chr13_+_75232797 2.502 NM_015842
LMO7
LIM domain 7
chr4_-_116254381 2.435 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr2_+_36777406 2.375 VIT
vitrin
chr3_-_115960807 2.369 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr2_+_66516196 2.312 MEIS1
Meis homeobox 1
chr4_-_176970407 2.310 GPM6A
glycoprotein M6A
chr7_-_27171673 2.234 NM_152739
HOXA9
homeobox A9
chr5_-_169340321 2.232 NM_001129891
FAM196B
family with sequence similarity 196, member B
chr17_-_10313600 2.225 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr3_+_116824840 2.204 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr7_-_83662152 2.186 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_+_160408447 2.175 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_+_18501876 2.163 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr2_-_144994038 2.161 ZEB2
zinc finger E-box binding homeobox 2
chr8_-_6407882 2.148 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr10_+_68355797 2.147 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr1_-_42157077 2.141 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr1_-_20682541 2.123


chr1_-_42156957 2.106 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr10_-_56230953 2.078 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr11_-_27679617 2.074 NM_170733
BDNF
brain-derived neurotrophic factor
chr9_+_117955890 2.069 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr3_-_64647325 2.066 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr8_-_72431274 2.065 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr1_-_202595666 2.063 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr3_-_11598829 2.056 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr3_-_21767819 2.048 NM_024697
ZNF385D
zinc finger protein 385D
chr2_-_121875610 2.035 CLASP1
cytoplasmic linker associated protein 1
chr8_+_70541631 2.029 SULF1
sulfatase 1
chr11_+_131285747 2.020 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr5_+_155686333 2.008 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr20_+_31613800 2.005 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr1_-_42156913 2.003


chr18_-_21185968 1.995 ZNF521
zinc finger protein 521
chr15_+_69626594 1.983 THSD4
thrombospondin, type I, domain containing 4
chr16_+_14187965 1.976 MKL2
MKL/myocardin-like 2
chr7_-_41709191 1.966 NM_002192
INHBA
inhibin, beta A
chr12_-_69317441 1.943 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr13_-_45323757 1.933 NM_198849
SIAH3
seven in absentia homolog 3 (Drosophila)
chr17_+_7732759 1.928 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr14_+_100365390 1.926 MEG3
maternally expressed 3 (non-protein coding)
chr17_-_44037332 1.893 NM_018952
HOXB6
homeobox B6
chr3_+_29297806 1.882 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr4_+_41309482 1.835 LIMCH1
LIM and calponin homology domains 1
chr3_-_79899748 1.824 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr4_+_54790190 1.815 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr10_-_126706442 1.811 NM_022802
CTBP2
C-terminal binding protein 2
chr8_+_70541412 1.805 NM_001128204
NM_015170
SULF1

sulfatase 1

chr18_-_39111243 1.805 NM_020783
SYT4
synaptotagmin IV
chr3_-_150578207 1.796 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr4_-_159312973 1.795 FAM198B
family with sequence similarity 198, member B
chr12_-_90100733 1.786 NM_001920
DCN
decorin
chr3_-_49372584 1.773 RHOA
ras homolog gene family, member A
chr17_-_36376663 1.762 NM_213656
KRT39
keratin 39
chr3_-_150578148 1.755 TM4SF1
transmembrane 4 L six family member 1
chr20_+_19903778 1.749 RIN2
Ras and Rab interactor 2
chr13_-_85271329 1.743 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr13_+_100902942 1.733 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr7_-_27108826 1.724 NM_006735
HOXA2
homeobox A2
chr18_-_21186107 1.723 NM_015461
ZNF521
zinc finger protein 521
chr9_-_116920232 1.723 NM_002160
TNC
tenascin C
chr4_+_183302105 1.721 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr6_+_12825818 1.703 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr8_-_13416554 1.676 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr10_-_118887801 1.665 NM_001112704
NM_199131
VAX1

ventral anterior homeobox 1

chr9_+_27099138 1.664 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr3_-_71376919 1.658 FOXP1
forkhead box P1
chr2_-_190635566 1.644 NM_005259
MSTN
myostatin
chr6_-_101018271 1.632 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chr3_-_150578103 1.624 TM4SF1
transmembrane 4 L six family member 1
chr16_+_65790514 1.620 NM_024712
ELMO3
engulfment and cell motility 3
chr6_-_138935359 1.617 NM_020464
NHSL1
NHS-like 1
chr2_+_101874765 1.584 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_135079120 1.566 NM_001159704
FHL1
four and a half LIM domains 1
chr18_-_44723116 1.531 NM_001190823
SMAD7
SMAD family member 7
chr1_+_160868932 1.501 DDR2
discoidin domain receptor tyrosine kinase 2
chrX_-_123925343 1.494 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1(Drosophila)


chr5_+_170668892 1.486 NM_021025
TLX3
T-cell leukemia homeobox 3
chr6_-_136888771 1.484 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr2_-_99284070 1.461 NM_174898
LYG1
lysozyme G-like 1
chr3_-_115380539 1.458 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr11_+_26972244 1.454 FIBIN
fin bud initiation factor homolog (zebrafish)
chr4_+_3341521 1.440 NM_198227
RGS12
regulator of G-protein signaling 12
chr14_-_94669547 1.423 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr15_+_94670160 1.419 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_-_5429702 1.417 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr6_+_108593907 1.414 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr4_-_74307637 1.389 ANKRD17
ankyrin repeat domain 17
chr6_+_136214495 1.385 NM_018945
PDE7B
phosphodiesterase 7B
chr7_-_83116414 1.385 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr18_+_64616296 1.379 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr3_-_11585264 1.370 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr4_-_123596921 1.368 NM_000586
IL2
interleukin 2
chr10_-_64698831 1.347 NM_004241
JMJD1C
jumonji domain containing 1C
chr3_+_129124591 1.346 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr11_+_26972203 1.342 NM_203371
FIBIN
fin bud initiation factor homolog (zebrafish)
chr9_-_94284571 1.330 NM_001193335
NM_017680
ASPN

asporin

chr3_+_158637273 1.327 NM_002852
PTX3
pentraxin 3, long
chr2_-_213724577 1.322 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr11_-_40272239 1.310 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr3_-_71860958 1.308 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr2_-_164300758 1.295 NM_018086
FIGN
fidgetin
chr4_-_40631397 1.292 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr6_-_136889302 1.291 MAP7
microtubule-associated protein 7
chr11_+_22652894 1.285 NM_005256
GAS2
growth arrest-specific 2
chr12_+_84198015 1.283 NM_006982
ALX1
ALX homeobox 1
chr11_-_85115105 1.282 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr2_-_144994349 1.279 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr4_+_41309668 1.263 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr7_+_110518297 1.260 NM_001099658
NM_001099660
NM_018334
LRRN3


leucine rich repeat neuronal 3


chr15_-_47042932 1.258 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr21_-_34820916 1.257 NM_203418
RCAN1
regulator of calcineurin 1
chr2_-_210726539 1.248 C2orf67
chromosome 2 open reading frame 67
chr13_-_35327798 1.244 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr5_+_152850276 1.244 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chrX_-_33139349 1.240 NM_004006
DMD
dystrophin
chr8_+_104900591 1.240 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr5_+_140742585 1.236 NM_018920
NM_032087
PCDHGA7

protocadherin gamma subfamily A, 7

chr16_+_81218142 1.236 CDH13
cadherin 13, H-cadherin (heart)
chr3_+_25445071 1.229 RARB
retinoic acid receptor, beta
chr2_-_77602843 1.228 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr6_+_21701942 1.218 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr7_-_27136876 1.215 NM_002141
HOXA4
homeobox A4
chr22_-_34564611 1.213 RPL41P5
ribosomal protein L41 pseudogene 5
chr3_+_69895651 1.213 NM_006722
MITF
microphthalmia-associated transcription factor
chr8_+_77756077 1.211 ZFHX4
zinc finger homeobox 4
chr12_+_88268845 1.211 LOC100131490
hypothetical LOC100131490
chr11_+_122936145 1.209 GRAMD1B
GRAM domain containing 1B
chr4_-_141293572 1.201 MAML3
mastermind-like 3 (Drosophila)
chr14_+_51025604 1.197 NM_001042481
FRMD6
FERM domain containing 6
chr11_+_124240491 1.194 NM_022370
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr12_-_90100679 1.193 DCN
decorin
chr6_+_12825022 1.188 PHACTR1
phosphatase and actin regulator 1
chr8_-_49996353 1.186 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr6_-_56824672 1.175 DST
dystonin
chr6_-_116488458 1.172 NM_002031
FRK
fyn-related kinase
chr3_-_150578023 1.170 TM4SF1
transmembrane 4 L six family member 1
chr21_-_38792173 1.161 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr4_-_186815116 1.155 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr20_-_1298493 1.151 FKBP1A
FK506 binding protein 1A, 12kDa
chr11_+_22652957 1.150 GAS2
growth arrest-specific 2
chr8_+_54926920 1.139 NM_170587
RGS20
regulator of G-protein signaling 20
chr12_-_90100710 1.133 DCN
decorin
chr7_+_134226727 1.129 CALD1
caldesmon 1
chr2_+_66516020 1.127 NM_002398
MEIS1
Meis homeobox 1
chr10_-_92671005 1.126 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_-_195302973 1.121 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr12_+_40117751 1.118 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr3_-_115825742 1.113 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr5_+_127012611 1.113 NM_001048252
CTXN3
cortexin 3
chr13_-_93929719 1.108 NM_001129889
NM_001922
DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)

chr17_-_44006808 1.105 NM_002146
HOXB3
homeobox B3
chr4_-_186814852 1.100 SORBS2
sorbin and SH3 domain containing 2
chr10_-_102978678 1.099 NM_006562
LBX1
ladybird homeobox 1
chr2_-_165768798 1.089 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr12_-_101036407 1.088 NM_024057
NUP37
nucleoporin 37kDa
chr8_+_77756061 1.088 NM_024721
ZFHX4
zinc finger homeobox 4
chr5_-_112658456 1.088 NM_002387
MCC
mutated in colorectal cancers
chr7_-_13996166 1.086 NM_001163147
NM_004956
ETV1

ets variant 1

chr4_-_176970895 1.080 GPM6A
glycoprotein M6A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 4.05e-28 GO:0007275 multicellular organismal development
1.39 1.31e-27 GO:0032502 developmental process
1.47 6.67e-27 GO:0048731 system development
1.31 8.19e-27 GO:0032501 multicellular organismal process
1.42 7.37e-25 GO:0048856 anatomical structure development
1.57 1.34e-18 GO:0007399 nervous system development
1.55 4.21e-17 GO:0009653 anatomical structure morphogenesis
1.43 1.35e-14 GO:0030154 cell differentiation
1.66 3.72e-14 GO:0022008 neurogenesis
1.41 6.73e-14 GO:0048869 cellular developmental process
1.44 7.40e-14 GO:0048513 organ development
1.66 5.87e-13 GO:0048699 generation of neurons
1.62 2.76e-12 GO:0050793 regulation of developmental process
1.37 3.06e-11 GO:0048523 negative regulation of cellular process
1.70 4.21e-11 GO:0045595 regulation of cell differentiation
1.66 4.97e-11 GO:2000026 regulation of multicellular organismal development
1.57 5.50e-11 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.66 4.57e-10 GO:0030182 neuron differentiation
1.56 8.16e-10 GO:0048468 cell development
1.32 3.84e-09 GO:0048519 negative regulation of biological process
1.63 6.00e-09 GO:0009790 embryo development
1.85 2.24e-08 GO:0043009 chordate embryonic development
1.84 2.26e-08 GO:0009792 embryo development ending in birth or egg hatching
1.54 2.96e-08 GO:0009888 tissue development
1.97 4.98e-08 GO:0061061 muscle structure development
1.90 5.44e-08 GO:0060284 regulation of cell development
1.60 8.53e-08 GO:0010628 positive regulation of gene expression
1.64 9.16e-08 GO:0009887 organ morphogenesis
1.65 1.36e-07 GO:0048666 neuron development
1.71 1.59e-07 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.97 1.74e-07 GO:0045596 negative regulation of cell differentiation
1.62 2.56e-07 GO:0000902 cell morphogenesis
1.61 3.27e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.68 3.40e-07 GO:0000904 cell morphogenesis involved in differentiation
1.55 3.99e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
1.60 4.89e-07 GO:0032989 cellular component morphogenesis
1.14 6.89e-07 GO:0050794 regulation of cellular process
2.08 9.36e-07 GO:0007517 muscle organ development
1.75 1.02e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.70 1.18e-06 GO:0048812 neuron projection morphogenesis
1.66 1.22e-06 GO:0031175 neuron projection development
1.57 1.57e-06 GO:0030030 cell projection organization
1.80 2.11e-06 GO:0007411 axon guidance
1.49 2.14e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.48 2.58e-06 GO:0006351 transcription, DNA-dependent
1.81 2.60e-06 GO:0051093 negative regulation of developmental process
1.69 3.05e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.48 3.49e-06 GO:0009891 positive regulation of biosynthetic process
1.12 3.93e-06 GO:0065007 biological regulation
1.13 4.43e-06 GO:0050789 regulation of biological process
1.69 4.83e-06 GO:0007409 axonogenesis
1.63 5.01e-06 GO:0032990 cell part morphogenesis
1.54 5.14e-06 GO:0051254 positive regulation of RNA metabolic process
1.63 5.22e-06 GO:0048858 cell projection morphogenesis
1.14 5.37e-06 GO:0050896 response to stimulus
1.38 5.98e-06 GO:0051239 regulation of multicellular organismal process
1.93 7.11e-06 GO:0003002 regionalization
1.44 7.19e-06 GO:0042127 regulation of cell proliferation
1.81 7.23e-06 GO:0022603 regulation of anatomical structure morphogenesis
2.22 1.14e-05 GO:0007156 homophilic cell adhesion
1.75 1.23e-05 GO:0007389 pattern specification process
1.48 1.55e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
1.49 1.84e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 2.30e-05 GO:0048518 positive regulation of biological process
1.76 2.36e-05 GO:0001501 skeletal system development
1.42 3.09e-05 GO:0032774 RNA biosynthetic process
1.58 3.75e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.57 4.52e-05 GO:0051253 negative regulation of RNA metabolic process
2.06 4.94e-05 GO:0009952 anterior/posterior pattern formation
1.80 5.58e-05 GO:0051960 regulation of nervous system development
2.74 6.34e-05 GO:0007519 skeletal muscle tissue development
1.24 7.86e-05 GO:0048522 positive regulation of cellular process
1.19 8.84e-05 GO:0023052 signaling
2.66 9.68e-05 GO:0060538 skeletal muscle organ development
1.83 1.02e-04 GO:0050767 regulation of neurogenesis
2.50 1.03e-04 GO:0048706 embryonic skeletal system development
1.40 1.10e-04 GO:0009605 response to external stimulus
1.61 1.20e-04 GO:0051094 positive regulation of developmental process
1.43 1.26e-04 GO:0040011 locomotion
1.36 1.47e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.51 1.65e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.12 1.69e-04 GO:0060537 muscle tissue development
1.49 1.73e-04 GO:0007167 enzyme linked receptor protein signaling pathway
2.74 1.84e-04 GO:0048634 regulation of muscle organ development
1.51 2.09e-04 GO:0010629 negative regulation of gene expression
1.58 2.30e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.58 2.41e-04 GO:0072358 cardiovascular system development
1.58 2.41e-04 GO:0072359 circulatory system development
1.29 2.86e-04 GO:0003008 system process
1.40 3.11e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.23 3.12e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.74 3.14e-04 GO:0016202 regulation of striated muscle tissue development
1.19 3.15e-04 GO:0060255 regulation of macromolecule metabolic process
1.23 3.32e-04 GO:0010468 regulation of gene expression
1.49 3.94e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.40 4.58e-04 GO:0031324 negative regulation of cellular metabolic process
1.19 4.72e-04 GO:0007165 signal transduction
1.33 4.75e-04 GO:0009893 positive regulation of metabolic process
2.14 4.75e-04 GO:0014706 striated muscle tissue development
1.48 6.39e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.00 6.51e-04 GO:0043062 extracellular structure organization
1.58 6.56e-04 GO:0032583 regulation of gene-specific transcription
1.22 9.24e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.33 9.64e-04 GO:0031325 positive regulation of cellular metabolic process
1.85 1.18e-03 GO:0045664 regulation of neuron differentiation
1.21 1.19e-03 GO:0071842 cellular component organization at cellular level
2.44 1.24e-03 GO:0022612 gland morphogenesis
1.45 1.25e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.23 1.48e-03 GO:0006355 regulation of transcription, DNA-dependent
3.74 1.69e-03 GO:0002053 positive regulation of mesenchymal cell proliferation
1.61 1.73e-03 GO:0048598 embryonic morphogenesis
1.72 1.89e-03 GO:0001568 blood vessel development
2.56 1.98e-03 GO:0051592 response to calcium ion
1.36 2.13e-03 GO:0009892 negative regulation of metabolic process
1.85 2.17e-03 GO:0048732 gland development
1.69 2.56e-03 GO:0035295 tube development
1.44 2.67e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.22 2.89e-03 GO:0051252 regulation of RNA metabolic process
1.41 2.89e-03 GO:0007155 cell adhesion
1.41 2.89e-03 GO:0022610 biological adhesion
1.50 3.21e-03 GO:0006935 chemotaxis
1.50 3.21e-03 GO:0042330 taxis
2.55 3.37e-03 GO:0048704 embryonic skeletal system morphogenesis
1.59 3.43e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.66 3.76e-03 GO:0048729 tissue morphogenesis
1.42 5.07e-03 GO:0009890 negative regulation of biosynthetic process
1.95 6.21e-03 GO:0050678 regulation of epithelial cell proliferation
1.54 6.81e-03 GO:0016477 cell migration
1.49 7.42e-03 GO:0048585 negative regulation of response to stimulus
1.56 7.75e-03 GO:0060429 epithelium development
1.37 8.04e-03 GO:0051128 regulation of cellular component organization
1.72 8.12e-03 GO:0048568 embryonic organ development
1.75 8.75e-03 GO:0048514 blood vessel morphogenesis
3.43 8.90e-03 GO:0010464 regulation of mesenchymal cell proliferation
1.15 1.06e-02 GO:0051716 cellular response to stimulus
2.32 1.06e-02 GO:2000027 regulation of organ morphogenesis
1.96 1.14e-02 GO:0042692 muscle cell differentiation
1.64 1.14e-02 GO:0001944 vasculature development
1.17 1.22e-02 GO:0016043 cellular component organization
1.89 1.30e-02 GO:0045165 cell fate commitment
1.47 1.34e-02 GO:0007417 central nervous system development
1.58 1.44e-02 GO:0045597 positive regulation of cell differentiation
1.06 1.61e-02 GO:0009987 cellular process
1.19 1.66e-02 GO:0031326 regulation of cellular biosynthetic process
1.46 1.69e-02 GO:0008284 positive regulation of cell proliferation
1.23 1.82e-02 GO:0010467 gene expression
3.13 2.14e-02 GO:0060688 regulation of morphogenesis of a branching structure
1.49 2.36e-02 GO:0023057 negative regulation of signaling
1.18 2.39e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.69 2.53e-02 GO:0002009 morphogenesis of an epithelium
1.71 2.73e-02 GO:0043193 positive regulation of gene-specific transcription
1.43 2.85e-02 GO:0006928 cellular component movement
1.18 2.97e-02 GO:0009889 regulation of biosynthetic process
4.22 2.98e-02 GO:0060428 lung epithelium development
1.31 3.01e-02 GO:0010646 regulation of cell communication
2.06 3.13e-02 GO:0030323 respiratory tube development
1.59 3.20e-02 GO:0016337 cell-cell adhesion
2.06 3.80e-02 GO:0030324 lung development
1.80 3.90e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.26 3.95e-02 GO:0009966 regulation of signal transduction
1.48 4.56e-02 GO:0010648 negative regulation of cell communication
1.24 4.63e-02 GO:0023051 regulation of signaling
1.98 4.65e-02 GO:0048736 appendage development
1.98 4.65e-02 GO:0060173 limb development
2.28 4.88e-02 GO:0051147 regulation of muscle cell differentiation
1.15 4.95e-02 GO:0080090 regulation of primary metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 4.10e-05 GO:0005886 plasma membrane
1.36 7.75e-05 GO:0044421 extracellular region part
1.16 1.69e-04 GO:0071944 cell periphery
1.65 1.70e-04 GO:0005578 proteinaceous extracellular matrix
1.58 3.52e-04 GO:0031012 extracellular matrix
1.53 1.14e-03 GO:0045202 synapse
1.76 1.49e-03 GO:0045111 intermediate filament cytoskeleton
1.36 1.93e-03 GO:0005615 extracellular space
1.80 2.32e-03 GO:0005882 intermediate filament
1.42 2.35e-03 GO:0030054 cell junction
1.94 5.62e-03 GO:0030016 myofibril
1.20 6.26e-03 GO:0044459 plasma membrane part
1.20 1.01e-02 GO:0005576 extracellular region
1.31 1.58e-02 GO:0042995 cell projection
1.89 1.71e-02 GO:0044449 contractile fiber part
1.22 1.79e-02 GO:0005856 cytoskeleton
1.24 2.60e-02 GO:0005654 nucleoplasm
1.83 2.72e-02 GO:0043292 contractile fiber
1.67 3.19e-02 GO:0030424 axon
1.44 3.45e-02 GO:0043005 neuron projection
1.56 3.69e-02 GO:0005667 transcription factor complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.63 1.80e-15 GO:0001071 nucleic acid binding transcription factor activity
1.63 1.80e-15 GO:0003700 sequence-specific DNA binding transcription factor activity
1.73 1.28e-13 GO:0043565 sequence-specific DNA binding
1.58 2.08e-13 GO:0030528 transcription regulator activity
1.12 3.85e-06 GO:0005515 protein binding
1.49 1.31e-05 GO:0005509 calcium ion binding
1.63 5.96e-05 GO:0000988 protein binding transcription factor activity
1.63 5.96e-05 GO:0000989 transcription factor binding transcription factor activity
1.62 9.88e-05 GO:0003712 transcription cofactor activity
1.95 5.05e-04 GO:0003714 transcription corepressor activity
1.76 1.39e-03 GO:0000975 regulatory region DNA binding
1.76 1.39e-03 GO:0001067 regulatory region nucleic acid binding
1.76 1.39e-03 GO:0044212 transcription regulatory region DNA binding
1.32 1.96e-03 GO:0005102 receptor binding
1.75 3.10e-03 GO:0010843 promoter binding
1.57 4.45e-03 GO:0016563 transcription activator activity
1.76 2.00e-02 GO:0008083 growth factor activity
2.94 2.82e-02 GO:0004435 phosphatidylinositol phospholipase C activity
1.51 3.25e-02 GO:0003779 actin binding